Chymotrypsin is a proteolytic enzyme prepared in a pure form from bovine pancreas. Chymotrypsin is then freeze-dried before packaging.
Properties
alpha Chymotrypsin possesses potent anti-inflammatory properties that enable to hasten the resorption of inflammatory oedemas as well as of postoperative and post-traumatic heamatomas and oedemas.
alpha Chymotrypsin, furthermore, possesses proteolytic properties that enable to destroy in situ the fibrinous formations resulting from subacute or chronic inflammatory processes.
Indications
All inflammatory conditions deep or superficial haematomas. In view of its enzymatic properties, alpha Chymotrypsin 5 mg is indicated in a very broad range of therapeutic applications:
In Surgery and Traumatology: Post-operative and post-fracture oedemas and haematomas, sprains.
In Gynaecology: Endo and exocervicitis, tubal sterility, chronic metritis and salpingitis, and post partum mammary engorgement
In Pneumology: Chronic bronchopathies, and suppurative pulmonary conditions.
In Oto-Rhino-Laryngology: Sinusitis, laryngitis and pharyngitis, adhesive otitis, and syringitis.
In Rheumatology: Arthritis, periarthritis, and Dupuytren’s contracture.
In Dermatology: Anthraxes, furuncles, abcesses, ulcers, eschars, and cheloid scars.
Dosage
1 or 2 ampoules daily, intramuscular, until disappearance of clinical signs.
Chronic conditions: 1 injection two or three times weekly.
Contraindications
known sensitivity to chymotrypsin.
Warnings
A sensitivity test should be made before injection.
Chymotrypsin is generally well tolerated, however, it may rarely induce allergic troubles in some patients, which necessitates the discontinuation of the medication and treatment (as any other allergic reaction) with B-adrenergic stimulant, corticosteroid, and antihistaminic.
Presentation
box of 3 ampoules of 5 mg crystallized and lyophilized chymotrypsin (450 E. A Units) + 3 ampoules of 3 ml apyrogenic saline.
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ALPHA CHEMOTRYPSIN INJECTION IM PATIENT INFORMATION LEAFLET
