صحة وجمال

Mupirax Ointment | Mupirocin 2%

Composition

Each gram of Mupirax ointment contains 20 mg mupirocin.

Pharmacodynamics

Mupirax, mupirocin, is a topical antibacterial agent which inhibits bacterial protein synthesis & RNA synthesis by binding to isoleucyl transfer-RNA synthetase.

It is mainly active against aerobic isolates of Staphylococcus aureus (including Methicillin-resistant & B-Iactamase producing strains). S. epidermidis, S. saprophyticus & Streptococcus pyogenes are susceptible to mupirocin.

It is also active against gram-negative organisms, such as Escherichia coli & Haemophilus influenzae. Mupirax shows no cross-resistance with other antibiotics.

Pharmacokintics

Mupirax has shown no measurable systemic absorption.

Its penetration into deeper epidermal & dermal layers of the skin is enhanced in traumatised skin & under occlusive dressings.

Indications

  • Treatment of primary & secondary superficial skin infections.
  • Treatment of various topical bacterial infections. such as impetigo, folliculitis & furunculosis caused by S. aureus (including Methicillin-resistant Staphylococcus aureus (MRSA), beta-hemolytic streptococcus, S. pyogenes.
  • Treatment of burn wound infections caused by MRSA infections.
  • Treatment of infected wounds & lacerations.
  • Side effects

    Mupirocin is usually well tolerated but local reactions such as burning, stinging, & itching may occur after its application to the skin.

    Contraindications

    Hypersensitivity reactions to Mupirax or other ointments containing polyethylene glycols.

    Mupirax ointment formulation is not suitable for ophthalmic or intranasal use.

    Precautions

    When Mupirax ointment is used on the face, avoid contact with the eyes.

    Open wounds: Polyethylene glycol can be absorbed from open wounds & damaged skin & is excreted by the kidney. As with other polyethylene based ointments, it should be used with caution if absorption of large quantities of polyethylene glycol is possible. & especially if there is evidence of moderate or severe renal impairment.

    Pregnancy: It should be used during pregnancy only if clearly needed, as there are no adequate and well-controlled studies in pregnant women.

    Lactation: It is not known whether mupirocin is excreted in human milk. Because many drugs are excreted in human milk. caution should be exercised to a nursing woman.

    Drug drug interactions

    The effect of the concurrent application of topical mupirocin ointment and other topical products has not been studied.

    Dosage & adminstration

    Adults & children: Mupirax ointment should be applied to the affected area up to three times daily for up to 10 days.

    The area may be covered with a gauze dressing if desired.

    Patient’s instractions

    Use this medication only as directed by your doctor.

    It is for external use only.

    Avoid contact with the eyes.

    The medication should be stopped & your doctor contacted if irritation, severe itching, or rash occurs.

    Presentation

    Mupirax ointment is supplied in tubes of 10 g and 30 g each.

    Store at room temperarure.

    Keep out of reach of children.

    Mupirax company

    GLOBAL NAPI PHARMACEUTICALS

    2nd  industrial Zone , 6th of October City· Egypt

    www.globolnapi.com


    السابق
    مصر- مالتي كير إيجيبت للصناعات الدوائية –
    التالي
    ميوبيراكس ۲% مرهم مضاد حيوي للجروح، الحروق، الدمامل، الخراريج، القروح،الحبوب