Composition: Each 1 ml or 1 gm contains:
Tobramycin ……… 3 mg
Properties
Tobrin contains tobramycin, a water-soluble aminoglycoside antibiotic, which is active against a wide variety of gram-negative and gram-positive ophthalmic pathogens. Spectrum of activity includes: Staphylococi, including S. aureus and S. epidermidis (coagulase-positive and coagulase -negative), including penicillin- resistant strains; Streptococci, including S.pneumoniae; Pseudomonas aeruginosa; Escherichia coli, Klebsiella pneumonia, Enterobacter aerogenes, Proteus species, Haemophilus influenzae, H. aegypticus, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species. Cross-resistance between tobramycin and gentamicin is generally seen, but about 10% of strains resistant to gentamicin are susceptible to tobramycin.
Tobrin ophthalmic preparations are safe and effective in children.
Indications
Treatment of external ocular infections caused by susceptible bacteria.
Dosage and Administration
Tobrin ophthalmic solution
Tobrin ophthalmic ointment
Tobrin ophthalmic ointment may be used in conjunction with Tobrin ophthalmic solution.
Tobrin ophthalmic preparations should be used only during one month after opening.
توبرين مرهم مضاد حيوى للعين
TOBRIN EYE DROP & OINTMENT PATIENT INFORMATION LEAFLET